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serpin Peptidase Inhibitor, Clade I (neuroserpin), Member 1 (SERPINI1) antibody

Antigen

serpin Peptidase Inhibitor, Clade I (neuroserpin), Member 1 (SERPINI1)

Synonyms PI12, neuroserpin, DKFZp781N13156, Ns, PI-12, Spi17, AI837402, Sp4, Spn4A, DmelCG9453, CG9453, raPIT5a, SERPINI1, pi12
Clonality Polyclonal
Host
Reactivity
Alternatives

Human

Application
Alternatives ELISA, Western Blotting (WB)
2 references available
Catalog no. ABIN185373
Quantity 100 ug
Price 501.80 $   Plus shipping costs $35.00
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Additional Information

Alternative name Neuroserpin
Gene ID 5274
Immunogen C-TMNTSGHDFEEL
Format Affinity-purified
Description All names and symbols: neuroserpin, SERPINI1, PI12, serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1, protease inhibitor 12 (neuroserpin). Official Symbol: SERPINI1. RefSeq number(s): NP_005016.1. Gene ontology terms: central nervous system development, peripheral nervous system development, serine-type endopeptidase inhibitor activity
Specificity Human, Mouse, Rat, Chimpanzee 410 aa

Application Details

Application Notes Peptide ELISA: antibody detection limit dilution 1:32,000. Western Blot: Approx 48kDa band observed in Human Brain lysate (calculated MW of 46.4kDa according to NP_005016.1). Recommended concentration: 1-3µg/ml.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Storage Aliquot and store at -20°C. Minimize freezing and thawing.
Research Area Neurology
Restrictions For Research Use only

Publications

Publications Onda, Belorgey, Sharp et al.: "Latent S49P neuroserpin forms polymers in the dementia familial encephalopathy with neuroserpin inclusion bodies." in: The Journal of biological chemistry, Vol. 280, Issue 14, pp. 13735-41, 2005 (PubMed).

Hasumi, Ishiguro, Nakamura et al.: "Neuroserpin (PI-12) is upregulated in high-grade prostate cancer and is associated with survival." in: International journal of cancer. Journal international du cancer, Vol. 115, Issue 6, pp. 911-6, 2005 (PubMed).

Alternatives

Alternatives for antigen "serpin Peptidase Inhibitor, Clade I (neuroserpin), Member 1 (SERPINI1)", type "Antibodies"
Hosts Mouse (40), Rabbit (18), Goat (12), Sheep (9)
Reactivities Human (45), Mouse (Murine) (25), Rat (Rattus) (18), Dog (Canine) (3), Rabbit (3), Cow (Bovine) (2), Chimpanzee (1)
Applications Enzyme Immunoassay (EIA) (54), Western Blotting (WB) (48), Immunohistochemistry (Frozen Sections) (IHC (fro)) (15), ELISA (Detection) (13), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (11), Radioimmunoassay (RIA) (6), Functional Studies (Func) (4), Immunoprecipitation (IP) (3), Blocking Antibody (Inhibition) (1), ELISA (1), ELISA (Capture) (1)
Conjugates Biotin (2), FITC (1), HRP (1)