Doublecortin Domain Containing 2 (DCDC2) (Internal Region) antibody

Details for Product No. ABIN185538
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Antigen
Synonyms DCDC2, zgc:123267, DCDC2A, RU2, RU2S, AW492955, Dcdc2
Epitope
Internal Region
(14), (7), (7), (6), (3), (2), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(37), (26), (15), (12), (2), (1)
Host
Goat
(35), (11), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Methode Type Peptide ELISA
Application
ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
(35), (21), (10), (5), (1)
Pubmed 2 references available
Quantity 100 μg
Options
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Catalog No. ABIN185538
374.27 $
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Immunogen Peptide with sequence C-DGEKANKDAEQKED, from the internal region of the protein sequence according to NP_057440.2.
Cross-Reactivity Dog (Canine), Pig (Porcine)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name DCDC2
Background Synonyms: DCDC2, doublecortin domain containing 2, HGNC:18141, KIAA1154, RU2, RU2S, DCDC2A
Gene ID 51473
NCBI Accession NP_057440
Research Area Neurology, Cytoskeleton
Application Notes ELISA: antibody detection limit dilution 1:4000.
Western blot: Full length recombinant human DCDC2 expressed in COS7 (Lane A), non-transfectant COS7 (lane B). Approx 52 kDa band observed (calculated MW of 52.8 kDa according to NP_057440.1). Data kindly provided by Wang and LoTurco, University of Connecticut, USA. Recommmended concentration 0.1-0.3 µg/mL. An anonymous customer found positive results in WB on Mouse brain tissue.
IHC: An anonymous customer found positive results in IHC on Rat retinal tissue. An anonymous customer found positive results in IHC on Rat dorsal root ganglion.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Supplier Images
anti-Doublecortin Domain Containing 2 (DCDC2) (Internal Region) antibody ABIN185538 (0.2µg/ml) staining of COS7 cell lysate transfected with full length recombinant human DCDC2 (A) and untransfected control COS7 cells (B). Primary incubation was 1 hour. Detected by chemiluminescence.
General Cope, Harold, Hill et al.: "Strong evidence that KIAA0319 on chromosome 6p is a susceptibility gene for developmental dyslexia." in: American journal of human genetics, Vol. 76, Issue 4, pp. 581-91, 2005 (PubMed).

Schumacher, Anthoni, Dahdouh et al.: "Strong genetic evidence of DCDC2 as a susceptibility gene for dyslexia." in: American journal of human genetics, Vol. 78, Issue 1, pp. 52-62, 2005 (PubMed).

Validation Images
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