Phosphodiesterase 4B (PDE4B) (C-Term) antibody

Details for Product No. ABIN185574, Supplier: Log in to see
Antigen
  • pde4b
  • fj87g04
  • wu:fj87g04
  • Dpde4
  • R74983
  • dunce
  • PDE4/IVb
  • Pde4B1
  • Pde4B2
  • Pde4B3
  • Pde4B4
  • phosphodiesterase 4B, cAMP-specific a
  • phosphodiesterase 4B, cAMP specific
  • pde4ba
  • Pde4b
Alternatives
anti-Human Phosphodiesterase 4B antibody for Western Blotting
Epitope
C-Term
10
2
Reactivity
Mouse (Murine)
23
15
13
Host
Goat
14
11
Clonality
Polyclonal
Conjugate
Un-conjugated
5
5
1
1
1
1
Method Type
Peptide ELISA
Application
ELISA, Western Blotting (WB)
24
22
13
4
3
Options
Supplier
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Immunogen Peptide with sequence C-DIDIATEDKSPVDT, from the C Terminus of the protein sequence according to NP_002591.2, NP_001032418.1, NP_001032416.1, NP_001032417.1.
Blocking Peptide Blocking peptide for this product available: ABIN368865
Specificity This antibody is expected to recognise all reported isoforms (NP_002591.2, NP_001032418.1, NP_001032416.1 and NP_001032417.1).
Cross-Reactivity Human, Rat (Rattus)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name Phosphodiesterase 4B (PDE4B Antibody Abstract)
Background Synonyms: PDE4B, phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila), RP5-876C12.1, DKFZp686F2182, DPDE4, MGC126529, PDEIVB, OTTHUMP00000046896, cAMP-specific 3%[yclic phosphodiesterase 4B, dunce-like phosphodiesterase E4, phosphodiesterase 4B, cAMP-specific, phosphodiesterase 4B, cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E4)
Gene ID 5142
NCBI Accession NP_001032417, NP_001032416, NP_002591, NP_001032418
Pathways Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction
Application Notes ELISA: antibody detection limit dilution 1:8000.
Western blot: Approx 85 kDa band observed in Mouse Brain lysates (calculated MW of 83.3 kDa according to Human NP_002591.2 and 82.1 kDa according to Mouse NP_062814.2). In transfected HEK293 transiently expressing Human PDE4B a band of approx. 85 kDa is observed. This band is not observed in the non-transfected HEK293. Recommended concentration: 0.5-1.0 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Supplier Images
 image for anti-Phosphodiesterase 4B (PDE4B) (C-Term) antibody (ABIN185574) ABIN185574 (0.5µg/ml) staining of Mouse Brain Lysate (35µg protein in RIPA buffer). P...
Background publications Millar, Pickard, Mackie, James, Christie, Buchanan, Malloy, Chubb, Huston, Baillie, Thomson, Hill, Brandon, Rain, Camargo, Whiting, Houslay, Blackwood, Muir, Porteous: "DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling." in: Science (New York, N.Y.), Vol. 310, Issue 5751, pp. 1187-91, 2005 (PubMed).

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