Cytokeratin 18 antibody
Quick Overview for Cytokeratin 18 antibody (ABIN187683)
Target
See all Cytokeratin 18 (KRT18) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- Reacts with a 45 kDa cytokeratin protein (cytokeratin 18). Keratin DA-7 specifically recongnizes glandular epithelial cells from gastro-intestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissue and mesothelial cells. It is not reactive with stratified squamous epithelia (esophagus, epidermis and ectocervix). In transitional epithelium of the bladder, it reacts only with the superficial (umbrella) cells. DA-7 can distinguish adenocarcinomas and mesotheliomas from squamous cell carcinoma and non-epithelial tumors. Species Reactivity: Human, does not recognize others.
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Isotype
- IgG1
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Application Notes
- ELISA Immunocytochemistry Immunohistochemistry (Protease pre-treatment required for paraffin-embedded tissue sections) Western blot The optimal dilution for a specific application should be determined by the researcher.
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Restrictions
- For Research Use only
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Buffer
- 100 µg in PBS containing 15 mM sodium azide, pH 7.4. Concentration is 1 mg/ml.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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- Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
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Alternative Name
- Cytokeratin 18
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Pathways
- Apoptosis, Caspase Cascade in Apoptosis
Target
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