KIRREL antibody (C-Term)
Quick Overview for KIRREL antibody (C-Term) (ABIN1881479)
Target
See all KIRREL (NEPH1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 505-534, C-Term
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Predicted Reactivity
- M, Rat
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This KIRREL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 505-534 amino acids from the C-terminal region of human KIRREL.
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Isotype
- Ig Fraction
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Application Notes
- WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Expiry Date
- 6 months
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- KIRREL (NEPH1) (Kin of IRRE Like 1 (NEPH1))
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Alternative Name
- KIRREL
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Background
- NEPH1 is a member of the nephrin-like protein family, which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2, MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003 [PubMed 12424224]).
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Molecular Weight
- 83536
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NCBI Accession
- NP_060710
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UniProt
- Q96J84
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Pathways
- Regulation of Actin Filament Polymerization
Target
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