KIRREL antibody (AA 17-200)

Catalog No. ABIN7268117

Product Details anti-KIRREL Antibody

Target: KIRREL (NEPH1) (Kin of IRRE Like 1 (NEPH1))

Binding Specificity: AA 17-200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIRREL antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: KIRREL Rabbit pAb

Sequence: QGTQTRFSQE PADQTVVAGQ RAVLPCVLLN YSGIVQWTKD GLALGMGQGL KAWPRYRVVG SADAGQYNLE ITDAELSDDA SYECQATEAA LRSRRAKLTV LIPPEDTRID GGPVILLQAG TPHNLTCRAF NAKPAATIIW FRDGTQQEGA VASTELLKDG KRETTVSQLL INPTDLDIGR VFTC

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 17-200 of human KIRREL (NP_060710.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KIRREL

Target: KIRREL (NEPH1) (Kin of IRRE Like 1 (NEPH1))

Alternative Name: KIRREL (NEPH1 Products)

Synonyms: NEPH1 antibody, 6720469N11Rik antibody, Kirrel1 antibody, Neph1 antibody, nephrin related antibody, kirre like nephrin family adhesion molecule 1 antibody, kin of IRRE like (Drosophila) antibody, Smp_104390 antibody, Smp_140170 antibody, KIRREL1 antibody, Kirrel antibody, Kirrel1 antibody

Background: NEPH1 is a member of the nephrin-like protein family, which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2, MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003 [PubMed 12424224]).[supplied by OMIM, Mar 2008],KIRREL,NEPH1,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,KIRREL

Molecular Weight: 72kDa/83kDa/85kDa

Gene ID: 55243

UniProt: Q96J84

Pathways: Regulation of Actin Filament Polymerization