RXFP1 antibody (C-Term)

Catalog No. ABIN1881770

Product Details anti-RXFP1 Antibody

Target: RXFP1 (Relaxin/insulin-Like Family Peptide Receptor 1 (RXFP1))

Binding Specificity: AA 685-713, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RXFP1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RXFP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 685-713 amino acids from the C-terminal region of human RXFP1.

Clone: RB41815

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-RXFP1 antibody (ABIN1881770)

Halls, Cooper: "Sub-picomolar relaxin signalling by a pre-assembled RXFP1, AKAP79, AC2, beta-arrestin 2, PDE4D3 complex." in: The EMBO journal, Vol. 29, Issue 16, pp. 2772-87, (2010) (PubMed).

Target Details for RXFP1

Target: RXFP1 (Relaxin/insulin-Like Family Peptide Receptor 1 (RXFP1))

Alternative Name: RXFP1 (RXFP1 Products)

Synonyms: LGR7 antibody, RXFPR1 antibody, Gm1018 antibody, Lgr7 antibody, RXFP2 antibody, relaxin/insulin like family peptide receptor 1 antibody, relaxin/insulin-like family peptide receptor 1 antibody, RXFP1 antibody, rxfp1 antibody, Rxfp1 antibody

Background: Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.

Molecular Weight: 86975

NCBI Accession: NP_001240657, NP_001240658, NP_067647

UniProt: Q9HBX9

Pathways: Myometrial Relaxation and Contraction