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SensoLyte® AMC Caspase Substrate Sampler Kit

FRET Fluorometric
Catalog No. ABIN1882428
  • Target See all Caspase (CASP) Kits
    Caspase (CASP)
    Detection Method
    Fluorometric
    Application
    Fluorescence Resonance Energy Transfer Microscopy (FRET)
    Brand
    SensoLyte®
    Characteristics
    The SensoLyte® Caspase Substrate Kit contains a series of AMC-based peptide substrates as fluorogenic indicators for assaying caspase protease activities. It provides the best solution for identifying a suitable substrate for designing AMC-based caspase assays. All the components in the kit are available in bulk package.
    Top Product
    Discover our top product CASP ELISA Kit
  • Comment

    FRET-based Assay Kit

    Restrictions
    For Research Use only
  • Handling Advice
    Keep Components A and B away from light
    Storage
    -20 °C
  • B?dziul, Jakubowicz-Gil, Paduch, G?owniak, Gawron: "Combined treatment with quercetin and imperatorin as a potent strategy for killing HeLa and Hep-2 cells." in: Molecular and cellular biochemistry, Vol. 392, Issue 1-2, pp. 213-27, (2014) (PubMed).

    B?dziul, Jakubowicz-Gil, Langner, Rzeski, G?owniak, Gawron: "The effect of quercetin and imperatorin on programmed cell death induction in T98G cells in vitro." in: Pharmacological reports : PR, Vol. 66, Issue 2, pp. 292-300, (2014) (PubMed).

    Jakubowicz-Gil, Langner, B?dziul, Wertel, Rzeski: "Apoptosis induction in human glioblastoma multiforme T98G cells upon temozolomide and quercetin treatment." in: Tumour biology, Vol. 34, Issue 4, pp. 2367-78, (2013) (PubMed).

  • Target
    Caspase (CASP)
    Alternative Name
    Caspase (CASP Products)
    Synonyms
    CG5370 Kit, DCP-1 Kit, DCP1 Kit, Dcp1 Kit, Dmel\\CG5370 Kit, ccp1 Kit, dcp-1 Kit, dcp1 Kit, l(2)01862 Kit, l(2)02132 Kit, Death caspase-1 Kit, Dcp-1 Kit
    Background
    Caspases play important roles in apoptosis and cell signaling. They are also identified as drug-screening targets. AMC-based substrates yield blue fluorescence upon protease cleavage (Ex/Em=354 nm/442 nm). They are widely used to monitor caspase activity.
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