RASD2 antibody (C-Term)

Catalog No. ABIN1887081

Product Details anti-RASD2 Antibody

Target: RASD2 (RASD Family, Member 2 (RASD2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASD2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the carboxy terminus of the human TEM2.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for RASD2

Target: RASD2 (RASD Family, Member 2 (RASD2))

Alternative Name: TEM2 (RASD2 Products)

Synonyms: RASD2 antibody, MGC:4834 antibody, Rhes antibody, TEM2 antibody, 4930526B11Rik antibody, AU045414 antibody, TEM-2 antibody, RASD family member 2 antibody, RASD family, member 2 antibody, RASD2 antibody, Rasd2 antibody

Background: Rhes, also known as tumor endothelial marker 2 (TEM2), is a small GTP-binding protein that is predominantly expressed in the striatal region of the brain.This protein belongs to the RASD subfamily of Ras-related GTP-binding protein superfamily and is thought to play a role in the normal development and function of the brain as mice lacking this gene showed increased anxiety levels and motor coordination deficits.Rhes was identified as TEM2 through analysis of genes whose expression was upregulated in tumor endothelium.Tumor endothelial markers are significantly up-regulated during angiogenesis and neoangiogenesis that are crucial for the growth of solid tumors.TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies.
Synonyms: Tumor endothelial marker 2, Ras homolog enriched in striatum, Rhes, RASD2

UniProt: Q96D21