PHOX2B antibody (Center)
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- Target See all PHOX2B Antibodies
- PHOX2B (Paired-Like Homeobox 2b (PHOX2B))
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Binding Specificity
- Center
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Reactivity
- Mouse, Human, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PHOX2B antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Cross-Reactivity (Details)
- PHOX2B antibody is predicted to not cross-react with other paired homeobox family members.
- Purification
- Affinity chromatography purified via peptide column
- Immunogen
- 15 amino acid peptide near the center of human PHOX2B.
- Top Product
- Discover our top product PHOX2B Primary Antibody
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS containing 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- Handling Advice
- Avoid freezing and thawing repeatly.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- Target
- PHOX2B (Paired-Like Homeobox 2b (PHOX2B))
- Alternative Name
- PHOX2B (PHOX2B Products)
- Synonyms
- phox2 antibody, xphox2b antibody, phox2b antibody, PHOX2B antibody, pmx2b antibody, nbphox antibody, NBLST2 antibody, NBPhox antibody, PMX2B antibody, Dilp1 antibody, Pmx2b antibody, paired-like homeobox 2b antibody, paired like homeobox 2b S homeolog antibody, paired-like homeobox 2bb antibody, paired like homeobox 2b antibody, phox2b antibody, phox2b.S antibody, phox2bb antibody, PHOX2B antibody, Phox2b antibody
- Background
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PHOX2A and PHOX2B (Paired mesoderm homeobox protein) are closely related, paired-homeodomain transcription factors that function as determinants of the noradrenergic phenotype during embryogenesis.PHOX2 proteins are crucial for the regulation of endogenous hydroxylases in neural crest cells and promote sympathetic neuron generation.Human PHOX2B contains one DNA binding homeobox domain and is required for the differentiation of all central and nonperipheral noradrenergic centers in the brain.In contrast, PHOX2A controls only the differentiation of the main noradrenergic center of the brain.Regulation of PHOX2 may have therapeutic utility in aging or disorders involving degeneration of noradrenergic neurons .
Synonyms: Paired-like homeobox 2B, Paired mesoderm homeobox protein 2B, PMX2B, Neuroblastoma Phox, NBLST2, NBPhox - NCBI Accession
- NP_003915
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