TYW3 antibody (Center)

Catalog No. ABIN1887669

Product Details anti-TYW3 Antibody

Target: TYW3 (tRNA-YW Synthesizing Protein 3 Homolog (TYW3))

Binding Specificity: Center

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TYW3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity (Details): TYW3 antibody is predicted to not cross-react with other TYW protein family members. At least two isoforms of TYW3 are known to exist, this antibody will detect both isoforms.

Purification: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide near the center of human TYW3.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for TYW3

Target: TYW3 (tRNA-YW Synthesizing Protein 3 Homolog (TYW3))

Alternative Name: TYW3 (TYW3 Products)

Synonyms: C1orf171 antibody, 5230400J09Rik antibody, tRNA-yW synthesizing protein 3 homolog L homeolog antibody, tRNA-yW synthesizing protein 3 homolog antibody, tRNA-yW synthesizing protein 3 homolog (S. cerevisiae) antibody, tyw3.L antibody, TYW3 antibody, Tyw3 antibody

Background: TYW3 is an enzyme that participates in the wybutosine-tRNA (Phe) biosynthesis pathway.Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome.TYW3 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation.
Synonyms: TYW3, Radical S-adenosyl methionine and flavodoxin domain-containing protein 3, tRNA wybutosine-synthesizing protein 3 homolog

UniProt: Q6IPR3