Calcyphosine 2 antibody (Center)

Catalog No. ABIN1887723

Product Details anti-Calcyphosine 2 Antibody

Target: Calcyphosine 2 (CAPS2)

Binding Specificity: Center

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calcyphosine 2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: This CAPS2 antibody is predicted to be specific to CAPS2 and not recognize CAPS1.

Purification: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid peptide near the center of the human CAPS2.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for Calcyphosine 2

Target: Calcyphosine 2 (CAPS2)

Alternative Name: CAPS2 (CAPS2 Products)

Synonyms: D630005B03Rik antibody, CAPS2 antibody, calcyphosine 2 antibody, calcyphosphine 2 antibody, CAPS2 antibody, Caps2 antibody, caps2 antibody

Background: CAPS2 and the related protein CAPS1 encode novel neural/endocrine-specific cytosolic and peripheral membrane proteins.Both are essential components of the synaptic vesicle priming machinery and are required for the Ca2+-regulated exocytosis of secretory vesicles, CAPS-deficient neurons contain no or very few fusion competent synaptic vesicles, causing a selective impairment of fast phasic transmitter release.Like CAPS1, numerous isoforms of CAPS2 are known to exist.These isoforms show distinct expression patterns in the brain.For example, CAPS2b showed high expression in the developing cerebellum.Furthermore, one version of CAPS2 mRNA that lacks exon 3 is detected in some autistic patients, suggesting that the differential expression pattern of CAPS2 is involved in neuronal development.
Synonyms: Calcium-dependent secretion activator 2, CADPS2

NCBI Accession: NP_060424