SYNPO2L antibody (N-Term)

Catalog No. ABIN1888124

Product Details anti-SYNPO2L Antibody

Target: SYNPO2L (Synaptopodin 2-Like (SYNPO2L))

Binding Specificity: N-Term

Reactivity: Mouse, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYNPO2L antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Purification: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid peptide near the amino terminus of human SYNPO2L.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for SYNPO2L

Target: SYNPO2L (Synaptopodin 2-Like (SYNPO2L))

Alternative Name: SYNPO2L (SYNPO2L Products)

Synonyms: 1110054M18Rik antibody, Chap antibody, synaptopodin 2 like antibody, synaptopodin 2-like antibody, SYNPO2L antibody, Synpo2l antibody

Background: SYNPO2L was initially identified as a novel heart-enriched gene that encodes a cytoskeletal protein highly expressed in the Z-disc of heart and skeletal muscle, associates with actin and interacts with a-actinin.It is a member of the synaptopodin family, sharing greatest homology with Synaptopodin 2.Recent studies have shown that SYNPO2L, while primarily localized to the sarcomere, can also translocate to the nucleus.A knockdown of SYNPO2L in zebrafish resulted in aberrant cardiac and skeletal muscle development and function, suggesting that it is a critical component of the sarcomere and plays an important role in muscle development.
Synonyms: Synaptopodin 2-like, cytoskeletal heart-enriched actin-associated protein, CHAP