Dipeptidyl-Peptidase 4 (DPP4) antibody

Antigen: Dipeptidyl-Peptidase 4 (DPP4)

Synonyms: CD26, ADABP, ADCP2, DPPIV, TP103, DPRP2, DPP IX, A330078I11, 6430584G11Rik, dpp9, im:7145318, DPP4, MGC81966, MOP9.8, MOP9_8, DKFZp469P1419, MGC172132, si:ch73-2d23.3

Clonality: Polyclonal

Host: Goat

Reactivity: Rat (Rattus)

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN190769

Additional Information

Alternative name: DPP4 / CD26

Gene ID: 1803, 13482 (mouse), 25253 (rat)

Immunogen: C-PPHFDKSKKYP

Format: Affinity-purified

Description: All names and symbols: DPP4, CD26, dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2) , ADABP, ADCP2, DPPIV, TP103 , T-cell activation antigen CD26, adenosine deaminase complexing protein 2, dipeptidylpeptidase 4 (CD26, adenosine deaminase complexing protein 2), dipeptidylpeptidase IV, dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2). Official Symbol: DPP4 . RefSeq number(s): NP_001926.2

Specificity: Human, Mouse, Rat, Dog

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:64,000. Approx 110kDa band observed in Rat Lung lysates (calculated MW of 88.3Da according to NP_001926.2). The observed molecular weight of this glycoprotein corresponds to earlier findings in literature with different antibodies (Herrera et al, J Biol Chem. 2001 Jun 1,276(22):19532-9., PMID: 11278278). Recommended concentration: 0.3-1µg/ml.

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Restrictions: For Research Use only

Images

ABIN190769 (0.3µg/ml) staining of Rat Lung lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Publications

Publications: Pei, Li, von Geldern et al.: "Discovery and structure-activity relationships of piperidinone- and piperidine-constrained phenethylamines as novel, potent, and selective dipeptidyl peptidase IV inhibitors." in: Journal of medicinal chemistry, Vol. 50, Issue 8, pp. 1983-7, 2007 (PubMed).