This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This FBXL17 Isoform 2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 262-297 amino acids from the C-terminal region of human FBXL17 Isoform 2.
Clone
RB47604
Isotype
Ig Fraction
Product Specific Information
What can the FBXL17 Antibody ABIN1944744 be used for?
This polyclonal FBXL17 Antibody detects FBXL17. The FBXL17 Antibody has been validated for various applications and can be used for the detection of FBXL17 and derivatives by Western Blotting, Immunohistochemistry (Paraffin-embedded Sections), Flow Cytometry.
What validation data is available for this FBXL17 Antibody?
The primary antibody is referenced in 3 publications and is characterized by a proven, very high reliability. It has currently 5 product images that show its performance in a variety of applications. The product is currently available in 80 μL, 400 μL quantities. FBXL17 Antibody for the detection of FBXL17 and derivatives.
What is the function of FBXL17?
Members of the F-box protein family, such as FBXL17, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1\; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008].