MEF2A antibody (pThr312)

Catalog No. ABIN196682

The Rabbit Polyclonal anti-MEF2A antibody is suitable to detect MEF2A in samples from Human. It has been validated for IF and IHC (p).

Quick Overview for MEF2A antibody (pThr312) (ABIN196682)

Target: MEF2A (Myocyte Enhancer Factor 2A (MEF2A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEF2A antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MEF2A Antibody

Binding Specificity: pThr312

Specificity: MEF2A (phospho-Thr312) antibody detects endogenous levels of MEF2A only when phosphorylated at threonine 312.

Purification: Immunoaffinity chromatography

Immunogen: Synthetic phosphopeptide derived from human MEF2A around the phosphorylation site of threonine 312 (L-A-TP-P-V).

Application Details

Application Notes: Suitable for use in Immunohistochemistry (1: 50approx. 1: 100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl containing 0.02 % Sodium Azide as preservative and 50 % glycerol as stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for MEF2A

Target: MEF2A (Myocyte Enhancer Factor 2A (MEF2A))

Alternative Name: MEF2A

Background: MEF2A (myocyte specific enhancer factor 2) belongs to a family of DNA binding regulatory proteins. The MEF2 family of transcription factors is highly expressed in the brain when neurons undergo dendritic maturation and synapse formation. MEF2A is especially abundant in granule neurons of the cerebellar cortex throughout the period of synaptogenesis. MEF2A also has key roles in cardiac and skeletal muscle development.Synonyms: MEF2, Myocyte-specific enhancer factor 2A, Serum response factor-like protein 1

Gene ID: 4205

NCBI Accession: NP_001124398

UniProt: Q02078

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades