Myocyte Enhancer Factor 2A (MEF2A) (AA 391-497) antibody

Details for Product No. ABIN1724919
Antigen
Epitope
AA 391-497
44
39
30
20
15
15
12
11
11
8
8
8
6
4
4
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
276
189
163
17
13
12
12
11
11
8
8
6
5
3
3
2
2
Host
Mouse
244
34
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
10
8
8
8
8
8
8
4
4
2
2
2
2
2
2
2
2
1
Application
ELISA, Western Blotting (WB)
176
118
94
69
58
26
14
10
8
7
6
2
Options
Immunogen Purified recombinant fragment of human MEF2A (AA 391-497) expressed in E. Coli.
Clone 2F9H2
Isotype IgG1
Purification Purified
Antigen
Alternative Name MEF2A (MEF2A Antibody Abstract)
Background The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene. ,
Molecular Weight 54.8 kDa
Gene ID 4205
HGNC 4205
Pathways Neurotrophin Signaling Pathway, Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
Image no. 1 for anti-Myocyte Enhancer Factor 2A (MEF2A) (AA 391-497) antibody (ABIN1724919) anti-Myocyte Enhancer Factor 2A (MEF2A) (AA 391-497) antibody (Image 1)
Image no. 2 for anti-Myocyte Enhancer Factor 2A (MEF2A) (AA 391-497) antibody (ABIN1724919) anti-Myocyte Enhancer Factor 2A (MEF2A) (AA 391-497) antibody (Image 2)
Image no. 3 for anti-Myocyte Enhancer Factor 2A (MEF2A) (AA 391-497) antibody (ABIN1724919) anti-Myocyte Enhancer Factor 2A (MEF2A) (AA 391-497) antibody (Image 3)
Product cited in: Zhao, Zhao, Peng: "The effects of myocyte enhancer factor 2A gene on the proliferation, migration and phenotype of vascular smooth muscle cells." in: Cell biochemistry and function, Vol. 30, Issue 2, pp. 108-13, 2012 (PubMed).

Guella, Rimoldi, Asselta, Ardissino, Francolini, Martinelli, Girelli, Peyvandi, Tubaro, Merlini, Mannucci, Duga: "Association and functional analyses of MEF2A as a susceptibility gene for premature myocardial infarction and coronary artery disease." in: Circulation. Cardiovascular genetics, Vol. 2, Issue 2, pp. 165-72, 2009 (PubMed).