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PKC mu antibody (pSer738)

The Rabbit Polyclonal anti-PKC mu antibody is suitable to detect PKC mu in samples from Human, Mouse and Rat. It has been validated for WB and IF.
Catalog No. ABIN196754
$588.00
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Quick Overview for PKC mu antibody (pSer738) (ABIN196754)

Target

See all PKC mu (PRKD1) Antibodies
PKC mu (PRKD1) (Protein Kinase D1 (PRKD1))

Reactivity

  • 128
  • 80
  • 69
  • 4
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  • 3
  • 2
  • 2
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  • 2
Human, Mouse, Rat

Host

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Rabbit

Clonality

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  • 12
Polyclonal

Conjugate

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This PKC mu antibody is un-conjugated

Application

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  • 1
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Western Blotting (WB), Immunofluorescence (IF)
  • Binding Specificity

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    pSer738

    Specificity

    PKD/PKCμ (phospho-Ser738) antibody detects endogenous levels of PKD/PKCμ only when phosphorylated at serine 738.

    Purification

    Immunoaffinity chromatography

    Immunogen

    Synsthetic phosphopeptide derived from human PKD/PKCmy around the phosphorylation site of serine 738 (E-K-SP-F-R).
  • Application Notes

    Western Blot: 1/500-1/1000. Immunofluorescence: 1/100-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freezing and thawing.

    Storage

    -20 °C

    Storage Comment

    Store the antibody (in aliquots) at -20 °C.
  • Target

    PKC mu (PRKD1) (Protein Kinase D1 (PRKD1))

    Alternative Name

    PRKD1

    Background

    Converts transient diacylglycerol. (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress through activation of NF-kappa-B.Synonyms: PKC D1, PKC mu, PKD, PKD1, PRKCM, Protein kinase C mu type, Protein kinase D, Serine/threonine-protein kinase D1, nPKC-D1, nPKC-mu

    Gene ID

    5587

    NCBI Accession

    NP_002733

    UniProt

    Q15139

    Pathways

    Myometrial Relaxation and Contraction
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