PKC mu antibody (pSer910)

Catalog No. ABIN7138729

Product Details anti-PKC mu Antibody

Target: PKC mu (PRKD1) (Protein Kinase D1 (PRKD1))

Binding Specificity: pSer910

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PKC mu antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of serine 910 (R-V-S(p)-I-L) derived from Human PKD/PKCm.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:1000, IF:1:100-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PKC mu

Target: PKC mu (PRKD1) (Protein Kinase D1 (PRKD1))

Alternative Name: PRKD1 (PRKD1 Products)

Synonyms: MGC83727 antibody, PRKD1 antibody, pkd antibody, pkcm antibody, prkcm antibody, pkc-mu antibody, PKC-MU antibody, PKCM antibody, PKD antibody, PRKCM antibody, PKD1 antibody, Pkcm antibody, Prkcm antibody, nPKC-D1 antibody, nPKC-mu antibody, PKC antibody, protein kinase D1 antibody, protein kinase D1 L homeolog antibody, PRKD1 antibody, prkd1.L antibody, prkd1 antibody, Prkd1 antibody

Background:

Background: Converts transient diacylglycerol. (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress through activation of NF-kappa-B.

Matthews SA, et al. J Biol Chem 1999 Sep, 274(37): 26543-26549
Brandlin I, et al. J Biol Chem 2002 Feb, 277(8): 6490-6496
Storz P, et al. Mol Pharmacol 2004 Oct, 66(4): 870-879

Aliases: KPCD1_HUMAN antibody, nPKC D1 antibody, nPKC mu antibody, nPKC-D1 antibody, nPKC-mu antibody, nPKCD1 antibody, nPKCmu antibody, PKC antibody, PKC MU antibody, PKCM antibody, PKCmu antibody, PKD 1 antibody, PKD antibody, PKD1 antibody, PRKCM antibody, PRKD 1 antibody, Prkd1 antibody, Protein kinase C mu antibody, Protein kinase C mu type antibody, Protein kinase D antibody, Protein kinase D1 antibody, Serine/threonine protein kinase D1 antibody, Serine/threonine-protein kinase D1 antibody

UniProt: Q15139

Pathways: Myometrial Relaxation and Contraction