Add to Basket
Order hotline:
+1 404 474 4654
+1 888 205 9894 (TF)

zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (pTyr493) antibody

Antigen

zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70)
Synonyms SRK, STD, TZK, ZAP-70, FLJ17670, FLJ17679, Srk, mur, 70kDa, mrtle, AI327364, MGC108902, zap70, MGC80670, MGC88962, ZAP70
Epitope
Alternatives

pTyr493
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Application
Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Catalog no. ABIN196887
Quantity 50 µg  (1.0 mg/ml)  (Variants)
Price 240.00 $   Plus shipping costs $35.00
Shipping to
Availability Ships within 7 to 10 Business Days

anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (pTyr493) antibody

Additional Information
Application Details Images Alternatives Secondary Antibodies Variants back to top

Characteristics Synonyms: ZAP-70, ZAP 70, SRK, 70 kDa zeta-associated protein, Syk-related tyrosine kinase
Alternative name ZAP70
Swiss-Prot P43403
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Description ZAP70, a 70 kDa member of the Syk tyrosine kinase family, plays a central role inlymphocyte activation and development, and is implicated in several immune disorders. Mutations in ZAP70 gene results in a form of Severe Combined ImmunodeficiencySyndrome (SCID) in humans. ZAP70 expression also defines a subset of ChronicLymphocytic Leukemia (CLL) in patients with unmutated Ig gene and poor clinical course.
Specificity This antibody detects endogenous levels of Zap-70 only when phosphorylated at Tyrosine493. Species: Human, Mouse and Rat. Others not tested.

Application Details
Images Alternatives Secondary Antibodies Variants back to top

Application Notes Western Blot 1/500-1/1000). Immunohistochemistry on Paraffin-Embedded Sections (1/50-1/100). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Concentration 1.0 mg/ml
Purification Aff - Purified
Buffer PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azideand 50% Glycerol.
Storage Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: One year from despatch.
Restrictions For Research Use only

Alternatives
Application Details Images Secondary Antibodies Variants back to top

Alternatives for antigen "zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70)", type "Antibodies"
Hosts Rabbit (99), Mouse (42)
Reactivities Human (136), Mouse (Murine) (65), Rat (Rattus) (59), Cow (Bovine) (18), Pig (Porcine) (18), Dog (Canine) (17), Horse (Equine) (16), Rabbit (16), Chicken (15), Guinea Pig (15)
Applications Western Blotting (WB) (78), Flow Cytometry (FACS) (37), Immunohistochemistry (IHC) (33), Immunofluorescence (IF) (32), ELISA (31), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (26), Enzyme Immunoassay (EIA) (12), Immunoprecipitation (IP) (11), Immunocytochemistry (ICC) (4), Immunohistochemistry (Frozen Sections) (IHC (fro)) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), ELISA (Detection) (1), Immunoelectron Microscopy (IEM) (1)
Conjugates Biotin (6), FITC (6), PE (3), HRP (2), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Alkaline Phosphatase (AP) (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1), RPE (1)
Epitopes pTyr319 (10), pTyr493 (7), Ab-319 (5), Ab-493 (5), C-Term (5), Center (3), Ab-292 (1), Ab-315 (1), pTyr292 (1), pTyr315 (1), pTyr492 (1)