Peptidyl-tRNA Hydrolase ICT1, Mitochondrial (AA 30-206) antibody (HRP)

Catalog No. ABIN1993482

Product Details

Target: Peptidyl-tRNA Hydrolase ICT1, Mitochondrial

Binding Specificity: AA 30-206

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Peptidyl-tRNA hydrolase ICT1, mitochondrial protein (30-206AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze.
Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details

Target: Peptidyl-tRNA Hydrolase ICT1, Mitochondrial

Alternative Name: MRPL58

Background:

Background: Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes.

Aliases: Digestion substraction 1 antibody, DS-1 antibody, DS1 antibody, Ict1 antibody, ICT1_HUMAN antibody, Immature colon carcinoma transcript 1 antibody, Immature colon carcinoma transcript 1 protein antibody, mitochondrial antibody, Peptidyl-tRNA hydrolase ICT1 antibody, Peptidyl-tRNA hydrolase ICT1, mitochondrial antibody

UniProt: Q14197