TNFRSF1B antibody
Quick Overview for TNFRSF1B antibody (ABIN199777)
Target
See all TNFRSF1B AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- Recognizes the extracellular part of human TNF-R II and with the soluble receptor. Minimal cross-reactivity is present with human TNF-alpha.
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Purification
- Purified
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Immunogen
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Human CD120b.
Type of Immunogen: Purified protein -
Isotype
- IgG
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Application Notes
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Approved: ELISA, Flo (1:10), IP, WB (1:10)
Usage: Suitable for use in ELISA, Western Blot, Flow Cytometry and Immunoprecipitation. The antibody is an agonistic antibody useful for detection of TNF-R II. The reactivity of the antibodies with cell bound or soluble TNF-Receptor is not inhibited by high concentrations of TNF-alpha. Western Blot: 1:10. Flow Cytometry: 1:10. Before use in biological assays, the product must be filter sterilized and depending on the concentration to be used dialyzed against culture medium to remove the sodium azide added. -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, 0.1 % BSA, 0.02 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
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Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.
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- TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))
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Alternative Name
- TNFRSF1B / TNFR2 / p75
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Background
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Name/Gene ID: TNFRSF1B
Family: TNF Receptor
Synonyms: TNFRSF1B, CD120b antigen, CD120b, Etanercept, p75 TNF receptor, Soluble TNFR1B variant 1, TNFBR, Tumor necrosis factor receptor, TNF-R-II, TNF-R75, TNFR2, p75TNFR, p80 TNF-alpha receptor, TBPII, TNF-R2, TNFR80, TNF-RII, TNFR-II, TNFR1B -
Gene ID
- 7133
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UniProt
- P20333
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Pathways
- NF-kappaB Signaling, Apoptosis, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Ubiquitin Proteasome Pathway
Target
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