ALIX antibody

Catalog No. ABIN206627

The Mouse Monoclonal anti-ALIX antibody is suitable to detect ALIX in samples from Human, Mouse, Rat and Xenopus laevis. It has been validated for WB, ELISA, IHC, IF, IP and IHC (p).

Quick Overview for ALIX antibody (ABIN206627)

Target: ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))

Reactivity: Human, Mouse, Rat, Xenopus laevis

Host: Mouse

Clonality: Monoclonal

Conjugate: This ALIX antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ALIX Antibody

Specificity: Recognizes apoptotic-linked-gene-product 2 (ALG-2) interacting protein X (ALIX), a conserved adaptor protein which is ubiquitously expressed. Alix was originally reported to play a role in apoptosis but has recently been shown to be involved in other cellular mechanisms including endosomal sorting, endocytosis, viral budding and actin cytoskeleton assembly.

Purification: Protein G purified

Immunogen: Alix fusion protein.

Type of Immunogen: Fusion protein

Isotype: IgG1

Application Details

Application Notes: Approved: ELISA, IF, IHC, IHC-P, IP, WB

Usage: Immunohistology: This product does not require protein digestion pre-treatment of paraffin sections.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for ALIX

Target: ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))

Alternative Name: PDCD6IP / ALIX

Background: Name/Gene ID: PDCD6IP

Synonyms: PDCD6IP, AIP1, ALG-2-interacting protein 1, ALIX, KIAA1375, PDCD6-interacting protein, ALG-2 interacting protein 1, DRIP4, HP95

Gene ID: 10015

UniProt: Q8WUM4

Pathways: p53 Signaling, EGFR Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Tube Formation