TNFRSF4 antibody
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- Target See all TNFRSF4 Antibodies
- TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
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Reactivity
- Cat
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This TNFRSF4 antibody is un-conjugated
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Application
- Western Blotting (WB), Flow Cytometry (FACS)
- Specificity
- Recognizes feline CD134, otherwise known as OX40, a 43kD type I membrane protein and member of the tumor necrosis factor receptor superfamily, expressed predominantly by CD4+ activated T cells, and a key regulator of T cell-dependent immune responses. CD134 has been identified as the receptor for the OX40 ligand, CD252, expressed by activated B cells, acting as a co-stimulatory signal for the stimulation and secretion of immunoglobulins. CD134 has also been identified as a binding receptor for Feline Immunodeficiency Virus (FIV), acting along with CXC chemokine receptor 4 (CXCR4) to facilitate the entry of the virus into CD4+ primary target cells.
- No Cross-Reactivity
- Mouse (Murine)
- Purification
- Protein A purified
- Immunogen
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CHO-derived feline CD134-Fc fusion protein.
Type of Immunogen: Fusion protein - Clone
- 7D6
- Isotype
- IgG1
- Top Product
- Discover our top product TNFRSF4 Primary Antibody
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- Application Notes
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Approved: Flo, WB (1 μg/mL)
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request. Western Blot: LS-C44970 detects a band of approximately 43kD. - Comment
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Target Species of Antibody: Cat
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Target
- TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
- Alternative Name
- TNFRSF4 / CD134 / OX40 (TNFRSF4 Products)
- Background
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Name/Gene ID: TNFRSF4
Family: TNF Receptor
Synonyms: TNFRSF4, ACT35 antigen, ATC35 antigen, CD134, ACT35, OX40, OX40 antigen, OX40L receptor, OX40 homologue, CD134 antigen, OX40 cell surface antigen, TXGP1L - Gene ID
- 7293
- UniProt
- P43489
- Pathways
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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