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Integrin Alpha2b antibody

CD41 Reactivity: Human, Primate FACS, IHC, IHC (fro) Host: Mouse Monoclonal HIP8 unconjugated

Catalog No. ABIN207081

Datasheet as PDF

Target See all Integrin Alpha2b (CD41) Antibodies

Integrin Alpha2b (CD41)
Reactivity
147

31

21

8

7

5

3

2

2

2

2

1

1

1

1

1
Human, Primate
Host
100

48

22

1
Mouse
Compatible Secondaries
Clonality
121

44

1
Monoclonal
Conjugate
64

18

14

13

6

4

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This Integrin Alpha2b antibody is un-conjugated
Application
126

45

30

25

21

21

13

13

10

9

8

5

2

1

1

1

1

1
Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity

Reacts with alpha (a) subunit of CD41 (heavy chain, 120 kD). CD41 is mainly expressed on platelets and megakaryocytes. The antibody HIP8 blocks platelet aggregation and completely inhibits ADP-, epinephrine-, and collagen-induced platelet activation, and partially inhibits ristocetin- and thrombin-induced platelet activation. HIP8 is useful in the morphological and physiological studies of platelets and megakaryocytes.

Purification

Protein G purified

Immunogen

Type of Immunogen: Native protein

Clone

HIP8

Isotype

IgG1

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anti-Integrin Alpha2b (CD41) (AA 351-450) antibody
CD41 Reactivity: Human, Rat FACS, WB, ELISA, IHC (fro), IHC (p), IF (p), IF (cc) Host: Rabbit Polyclonal unconjugated

anti-Integrin Alpha2b (CD41) antibody
CD41 Reactivity: Mouse FACS, ELISA, IHC (fro), IP, IHC (p) Host: Rat Monoclonal MWReg30 unconjugated

anti-Integrin Alpha2b (CD41) antibody
CD41 Reactivity: Mouse FACS, ELISA, IHC (fro), IP, IHC (p), Func Host: Rat Monoclonal MWReg30 unconjugated

anti-Integrin Alpha2b (CD41) antibody
CD41 Reactivity: Human, Non-Human Primate FACS, IHC (fro) Host: Mouse Monoclonal HIP2 unconjugated

anti-Integrin Alpha2b (CD41) antibody (Biotin)
CD41 Reactivity: Human FACS Host: Mouse Monoclonal MEM-06 Biotin

anti-Integrin Alpha2b (CD41) antibody (FITC)
CD41 Reactivity: Human FACS Host: Mouse Monoclonal MEM-06 FITC

anti-Integrin Alpha2b (CD41) (AA 677-711), (C-Term) antibody
CD41 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Integrin Alpha2b (CD41) antibody
CD41 Reactivity: Human, Non-Human Primate FACS, IHC (fro) Host: Mouse Monoclonal HIP8 unconjugated

Application Notes

Approved: Flo, IHC, IHC-Fr

Usage: Flow Cytometry: This HIP8 antibody has been tested by flow cytometric analysis of human platelets. This can be used at less than or equal to 0.5 μg per 100 μL blood (per 106cells).

Not recommended for: IHC-P

Comment

Target Species of Antibody: Human

Restrictions

For Research Use only
Format

Liquid

Concentration

Lot specific

Buffer

PBS, 15 mM sodium azide, approx,  pH 7.4.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice

Avoid repeated freezing and thawing.

Storage

4 °C,-20 °C

Storage Comment

4°C or -20°C, Avoid freeze-thaw cycles.
Target

Integrin Alpha2b (CD41)

Alternative Name

ITGA2B / CD41 (CD41 Products)

Background

Name/Gene ID: ITGA2B
Family: Integrin

Synonyms: ITGA2B, BDPLT2, CD41B, GT, gp2B, Integrin alpha-IIb, ITGAB, GPIIb, HPA3, Platelet-specific antigen BAK, CD41, CD41 antigen, GPalpha IIb, GTA

Gene ID

3674

UniProt

P08514

Pathways

Integrin Complex