beta-2 Microglobulin antibody (Biotin)
Quick Overview for beta-2 Microglobulin antibody (Biotin) (ABIN207214)
Target
See all beta-2 Microglobulin (B2M) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- Reacts with beta2-microglobulin (beta2M) associated with cell-surface MHC Class I molecules and other membrane antigens as well as with soluble beta2-microglobulin. beta2M is a 12 kD Ig like glycoprotein expressed on lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells and epithelial cells. It is absent on erythrocytes.
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Purification
- Protein A purified
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Immunogen
- Purified isolated human beta2-microglobulin.
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Isotype
- IgG1
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Application Notes
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Approved: Flo (1:200), IF (1:200)
Usage: Biotinylated antibody is designed for indirect immunofluorescence analysis by Flow Cytometry. Suggested working dilution is 1:200. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, 15 mM sodium azide, approx, pH 7.4.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- avoid freeze thaw cycles.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
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- beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
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Alternative Name
- B2M / Beta 2 Microglobulin
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Background
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Name/Gene ID: B2M
Synonyms: B2M, Beta 2 Microglobulin, Beta-2-microglobulin, Beta-2-microglobin -
Gene ID
- 567
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UniProt
- P61769
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Pathways
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
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