ARPC4 antibody (N-Term)

Catalog No. ABIN2156404

This Rabbit Polyclonal antibody specifically detects ARPC4 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae and Zebrafish (Danio rerio).

Quick Overview for ARPC4 antibody (N-Term) (ABIN2156404)

Target: ARPC4 (Actin Related Protein 2/3 Complex, Subunit 4, 20kDa (ARPC4))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARPC4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ARPC4 Antibody

Binding Specificity: N-Term

Purpose: ARPC4 Antibody - N-terminal region

Sequence: VERHNKPEVE VRSSKELLLQ PVTISRNEKE KVLIEGSINS VRVSIAVKQG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%, Yeast: 92%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against ARPC4-TTLL3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human ARPC4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33130-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ARPC4

Target: ARPC4 (Actin Related Protein 2/3 Complex, Subunit 4, 20kDa (ARPC4))

Alternative Name: ARPC4

Background:

Background Information: This gene encodes one of seven subunits of the human Arp2/3 protein complex. This complex controls actin polymerization in cells and has been conserved throughout eukaryotic evolution. This gene encodes the p20 subunit, which is necessary for actin nucleation and high-affinity binding to F-actin. Alternative splicing results in multiple transcript variants. Naturally occurring read-through transcription exists between this gene and the downstream tubulin tyrosine ligase-like family, member 3 (TTLL3), which results in the production of a fusion protein.

Gene Name: actin related protein 2/3 complex subunit 4

Alternative Symbols: ARC20, P20-ARC

Protein Name: actin-related protein 2/3 complex subunit 4

Molecular Weight: 19kDa

Gene ID: 10093

NCBI Accession: NP_001020130

UniProt: P59998

Pathways: RTK Signaling, Regulation of Actin Filament Polymerization