Reticulon 4 antibody (N-Term)
Quick Overview for Reticulon 4 antibody (N-Term) (ABIN6736514)
Target
See all Reticulon 4 (RTN4) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Specificity
- Recognizes Neurite Outgrowth Inhibitor Protein C (NogoC). Species sequence Homology: human Nogo-C/foocen-S/RTN 4:100 % , mouse Nogo-C/foocen-S/RTN 4:81 %. Most of this region is unique to Nogo-C and not conserved in Nogo-A/B isoforms.
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Purification
- Immunoaffinity purified
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Immunogen
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An 11aa peptide within the N-terminal, extracellular domain of human Nogo-C.(KLH coupled).
Type of Immunogen: Synthetic peptide -
Isotype
- IgG
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Application Notes
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Approved: ELISA (1:10000 - 1:100000), WB (1 - 10 μg/mL)
Usage: Suitable for use in ELISA and Western Blot. ELISA: 1:10000-1:100000 using 50-100 ng of control peptide/well. Western Blot: 1-10 μg/mL using ECL. -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, pH 7.4, 0.1 % BSA, 0.05 % sodium azide, 40 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Reticulon 4 (RTN4)
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Alternative Name
- RTN4 / Nogo
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Background
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Name/Gene ID: RTN4
Family: Reticulon
Synonyms: RTN4, Human NogoA, My043 protein, Neurite outgrowth inhibitor, NOGOC, NSP-CL, Nogo protein, KIAA0886, Reticulon 5, Reticulon-4, Reticulon-5, Reticulon 4, RTN4-B1, RTN-X, RTN4-A, RTN4-B2, RTN4-C, Nbla00271, Neurite growth inhibitor 220, NI220/250, NOGO-A, Nogo-C, ASY, Foocen, Nbla10545, NOGO, Nogo-B, NSP -
Gene ID
- 57142
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UniProt
- Q9NQC3
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Pathways
- Neurotrophin Signaling Pathway, Regulation of Cell Size, SARS-CoV-2 Protein Interactome
Target
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