Keratin 4/5/6/8/10/13/18 (KRT4/5/6/8/10/13/18) antibody (PE)

Antigen: Keratin 4/5/6/8/10/13/18 (KRT4/5/6/8/10/13/18)

Clonality: Monoclonal (C-11)

Host: Mouse

Conjugate: PE

Application: Flow Cytometry (FACS)

Catalog no.: ABIN238395

Additional Information

Characteristics: Synonyms: pan Keratin, Cytokeratin Pan-reactive

Alternative name: Cytokeratin (pan) (4+5+6+8+10+13+18)

Immunogen: Keratin-enriched preparation from human epidermoid carcinoma cell line A431.

Isotype: IgG1

Clone: C-11

Description: Cytokeratins are a subfamily of intermediate filaments and characterized by remarkablebiochemical diversity. Cytokeratins are represented in epithelial tissues by at least 20different polypeptides, molecular weight between 40 kDa and 68 kDa. The individualcytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidiccytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.

Specificity: The antibody C-11 reacts with Cytokeratin peptides 4, 5, 6, 8, 10, 13, 18. Cytokeratins are amember of intermediate filaments subfamily represented in epithelial tissues.

Application Details

Application Notes: Suitable for Flow Cytometry analysis. It is recommended to use 10-20 μl of antibodyconjugate per 10e6 cells (100 μl cell suspension). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Concentration: 0.1 mg/ml

Buffer: PBS containing 15 mM sodium azide as preservative and 0.2% (w/v)high-grade BSA (Protease free) as stabilizer.Label: Conjugated with R-Phycoerythrin (PE) under optimum conditions

Storage: Store the antibody in the dark at 2-8°C. DO NOT FREEZE! Avoid prolonged exposure to light. Shelf life: one year from despatch.

Restrictions: For Research Use only