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Antibodies
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anti-CD36 Molecule (thrombospondin Receptor) (CD36) antibody
CD36 Molecule (thrombospondin Receptor) (CD36) antibody
| Antigen |
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| Synonyms |
FAT, GP4, GP3B, GPIV, CHDS7, PASIV, SCARB3 |
| Clonality |
Monoclonal (TR9) |
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Host
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Reactivity
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Application
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Flow Cytometry (FACS) (114), Western Blotting (WB) (48), Immunohistochemistry (Frozen Sections) (IHC (fro)) (40), Immunoprecipitation (IP) (34), Immunofluorescence (IF) (29), Immunohistochemistry (IHC) (23), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (18), ELISA (15), Blocking Antibody (Inhibition) (7), Enzyme Immunoassay (EIA) (5), Functional Studies (Func) (5), Immunohistochemistry (Fixed) (IHC (fx)) (5), Immunocytochemistry (ICC) (3), Neutralization (Neut) (3), Blocking Antibody (Inhibition) (1), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (1)
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| Catalog no. |
ABIN238510 |
| Quantity |
0.1 mg (1.0 mg/ml) |
| Price |
265.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: Glycoprotein IIIb, PAS IV, PAS-4, Thrombospondin receptor, GP3B, GP4, Plateletglycoprotein 4, Platelet glycoprotein IV, Platelet collagen receptor, Fatty acid translocase
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Alternative name
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CD36
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Swiss-Prot
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P16671
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Immunogen
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Platelets.
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Cross-Reactivity
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Human
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Isotype
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IgG1 (Matching secondary antibodies)
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Clone
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TR9
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Description
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CD36 (fatty acid translocase, FAT) is an 88 kDa ditopic glycosylated protein that belongs tothe class B family of scavenger receptors. CD36 is expressed by most resting marginal zoneB cells but not by follicular and B1 B cells, and it is rapidly induced on Follicular B cells invitro upon TLR and CD40 stimulation. CD36 does not affect the development of B cells, butmodulates both primary and secondary antibody response. Similarly to glucose transporterGLUT4, CD36 is translocated from intracellular pools to the plasma membrane followingcell stimulation by insulin. In mouse, CD36 is responsible for gustatory perception oflong-chain fatty acids.
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Specificity
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The antibody TR9 reacts with CD36 (GPIIIb), a 85 kDa integral membrane glycoproteinexpressed on platelets, macrophages, endothelial cells, early erythroid cells andmegakaryocytes. This antibody cross-blocks binding of FITC-labeled standard antibody OKM5. Anti-CD36 antibodies inhibit adhesive functions (e. g. adherence of infected erythrocytes totarget cells). Species: Human. Others not tested.
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Application Notes
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Flow Cytometry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Concentration
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1.0 mg/ml
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Purification
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Purified
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Buffer
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20 mM Tris/HCl, pH~7.4 with 15 mM Sodium Azide as preservative
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Storage
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Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid freeze/thaw cycles. Shelf life: One year from despatch.
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Research Area
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Cancer, Atherosclerosis, Hematopoietic Progenitors, Hematopoietic Stem Cells, CD Antigens, Surface Receptors of Immune Cells
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Restrictions
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For Research Use only
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Alternatives for antigen "CD36 Molecule (thrombospondin Receptor) (CD36)", type "Antibodies"
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Hosts
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Mouse (130), Rabbit (15), Rat (13), Goat (1)
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Reactivities
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Human (119), Mouse (Murine) (25), Rat (Rattus) (5), Monkey (1), Pig (Porcine) (1)
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Applications
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Flow Cytometry (FACS) (114), Western Blotting (WB) (48), Immunohistochemistry (Frozen Sections) (IHC (fro)) (40), Immunoprecipitation (IP) (34), Immunofluorescence (IF) (29), Immunohistochemistry (IHC) (23), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (18), ELISA (15), Blocking Antibody (Inhibition) (7), Enzyme Immunoassay (EIA) (5), Functional Studies (Func) (5), Immunohistochemistry (Fixed) (IHC (fx)) (5), Immunocytochemistry (ICC) (3), Neutralization (Neut) (3), Blocking Antibody (Inhibition) (1), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (1)
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Conjugates
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FITC (25), PE (7), Biotin (6), APC (3), RPE (2), HRP (1)
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Epitopes
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extracellular domain (6), transcript variant 3 (3), Center (1)
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Alternatives 
