CD36 antibody (PE)

Catalog No. ABIN238511

Product Details anti-CD36 Antibody (PE)

Target: CD36

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD36 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Characteristics: Synonyms: Glycoprotein IIIb, PAS IV, PAS-4, Thrombospondin receptor, GP3B, GP4, Plateletglycoprotein 4, Platelet glycoprotein IV, Platelet collagen receptor, Fatty acid translocase

Purification: Size-Exclusion Chromatography.

Immunogen: Platelets.

Clone: TR9

Isotype: IgG1

Application Details

Application Notes: Suitable for Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 μL ofwhole blood or 10^6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 15 mM sodium azide as preservative and 0.2 % (w/v) high-grade BSA (Protease free) as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody in the dark at 2-8 °C. DO NOT FREEZE! Avoid prolonged exposure to light.
Shelf life: One year from despatch.

Expiry Date: 12 months

Target Details for CD36

Target: CD36

Alternative Name: CD36 (CD36 Products)

Synonyms: BDPLT10 antibody, CHDS7 antibody, FAT antibody, GP3B antibody, GP4 antibody, GPIV antibody, PASIV antibody, SCARB3 antibody, Fat antibody, Scarb3 antibody, GPIIIB antibody, PAS-4 antibody, zgc:92513 antibody, CD36 molecule antibody, CD36 molecule (thrombospondin receptor) antibody, CD36 antibody, Cd36 antibody, cd36 antibody

Background: CD36 (fatty acid translocase, FAT) is an 88 kDa ditopic glycosylated protein that belongs to the class B family of scavenger receptors. CD36 is expressed by most resting marginal zone B cells but not by follicular and B1 B cells, and it is rapidly induced on Follicular B cells in vitro upon TLR and CD40 stimulation. CD36 does not affect the development of B cells, but modulates both primary and secondary antibody response. Similarly to glucose transporter GLUT4, CD36 is translocated from intracellular pools to the plasma membrane following cell stimulation by insulin. In mouse, CD36 is responsible for gustatory perception of long-chain fatty acids.Synonyms: Fatty acid translocase, GP3B, GP4, Glycoprotein IIIb, PAS IV, PAS-4, Platelet collagen receptor, Platelet glycoprotein 4, Platelet glycoprotein IV, Thrombospondin receptor

UniProt: P16671

Pathways: TLR Signaling, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades, Lipid Metabolism, S100 Proteins