Add to Basket
Order hotline:
+1 404 474 4654
+1 888 205 9894 (TF)

Tumor Necrosis Factor Receptor Superfamily Member 10d (TNFRSF10D) antibody

Antigen

Tumor Necrosis Factor Receptor Superfamily Member 10d (TNFRSF10D)
Synonyms DCR2, CD264, TRUNDD, TRAILR4, TNFRSF10D
Clonality Monoclonal (TRAIL-R4-01)
Host
Alternatives

Mouse
Reactivity
Alternatives

Human
Application
Alternatives Flow Cytometry (FACS)
Catalog no. ABIN238513
Quantity 0.1 mg  (1.0 mg/ml)
Price 290.00 $   Plus shipping costs $35.00
Shipping to
Availability Ships within 7 to 10 Business Days

Additional Information
Application Details Alternatives Secondary Antibodies back to top

Characteristics Synonyms: TNFRSF10D, DCR2, TRAIL-R4, TRUNDD, Decoy receptor 2, TRAIL receptor 4, Tumor necrosisfactor receptor superfamily member 10D, TNF-related apoptosis-inducing ligand receptor 4,TRAIL receptor with a truncated death domain
Alternative name CD264 / TRAILR4
Swiss-Prot Q9UBN6
Immunogen TRAIL-R4 (aa 1-210) - hIgGhc fusion protein.
Cross-Reactivity Human
Isotype IgG1  (Matching secondary antibodies)
Clone TRAIL-R4-01
Description TRAIL-R4 (CD264, TR4, DcR2, TRUNDD), expressed mainly on CD8+ and NK cells, belongs toreceptors of TRAIL, a TNF-like membrane toxic protein that induces apoptosis in manytumour cells, but not in normal cells. TRAIL-R4, however, contains partially truncated deathdomain, thus it is unable to induce apoptosis and serves as a negative regulator ofapoptotic signaling by impairment death-inducing signaling complex (DISC) processing. TRAIL-R4 interacts with death receptor 5 (DR5) in the native DISC in a TRAIL-dependentmanner and prevents its corecruitment with death receptor 4 (DR4).
Specificity The antibody TRAIL-R4-01 reacts with TRAIL-R4, a 42 kDa transmembrane protein expressedon various blood cells. Species: Human. Others not tested.

Application Details
Alternatives Secondary Antibodies back to top

Application Notes Suitable for use in Flow Cytometry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Concentration 1.0 mg/ml
Purification Azide Free
Buffer PBS, pH 7.4 without preservatives.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid freeze/thaw cycles. Shelf life: One year from despatch.
Research Area Signaling, Apoptosis/Necrosis
Restrictions For Research Use only

Alternatives
Application Details Secondary Antibodies back to top

Alternatives for antigen "Tumor Necrosis Factor Receptor Superfamily Member 10d (TNFRSF10D)", type "Antibodies"
Hosts Rabbit (8), Mouse (7), Goat (1)
Reactivities Human (16), Mouse (Murine) (1), Rat (Rattus) (1)
Applications Western Blotting (WB) (9), Flow Cytometry (FACS) (6), Immunofluorescence (IF) (5), Enzyme Immunoassay (EIA) (4), Immunohistochemistry (Frozen Sections) (IHC (fro)) (3), Immunoprecipitation (IP) (2), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (1)
Conjugates FITC (1), PE (1)