Retinoic Acid Receptor Responder (Tazarotene Induced) 3 (RARRES3) (AA 124-136) antibody

Antigen: Retinoic Acid Receptor Responder (Tazarotene Induced) 3 (RARRES3)

Synonyms: RIG1, TIG3, HRASLS4, MGC8906, PLA1/2-3, MGC68773, RARRES3

Epitope: AA 124-136

Clonality: Polyclonal

Host: Goat

Application: ELISA

Catalog no.: ABIN238674

Additional Information

Alternative name: RIG1 / RARRES3 (aa 124 to 136)

Gene ID: 5920

Immunogen: KSRCKQVEKAKVE

Format: Affinity-purified

Description: All names and symbols: RARRES3, retinoic acid receptor responder (tazarotene induced) 3 , HRASLS4, MGC8906, RIG1, TIG3. Official Symbol: RARRES3 . RefSeq number(s): NP_004576.2

Specificity: Human

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:128,000. Western Blot: Preliminary experiments gave bands at approx 22kDa and 55kDa in Human Thymus lysates after 1µg/ml antibody staining. The 55kDa band was observed in all tissues tested. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 18.8kDa according to NP_004576.2. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands). We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Restrictions: For Research Use only

Publications

Publications: Tsai, Shyu, Jiang: "RIG1 suppresses Ras activation and induces cellular apoptosis at the Golgi apparatus." in: Cellular signalling, Vol. 19, Issue 5, pp. 989-99, 2007 (PubMed).