RFX2 antibody

Catalog No. ABIN2458290

Product Details anti-RFX2 Antibody

Target: RFX2 (Regulatory Factor X 2 (RFX2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RFX2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RFX2.

Application Details

Application Notes: RFX2 antibody can be used for detection of RFX2 by ELISA at 1:1562500. RFX2 antibody can be used for detection of RFX2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store RFX2 antibody at -20 °C.

Target Details for RFX2

Target: RFX2 (Regulatory Factor X 2 (RFX2))

Alternative Name: RFX2 (RFX2 Products)

Synonyms: 5430432H19Rik antibody, cb133 antibody, sb:cb133 antibody, sb:cb7 antibody, wu:fd20b11 antibody, zfx2 antibody, zgc:91808 antibody, regulatory factor X2 antibody, regulatory factor X, 2 (influences HLA class II expression) antibody, regulatory factor X2 S homeolog antibody, RFX2 antibody, Rfx2 antibody, rfx2.S antibody, rfx2 antibody

Background: RFX2 is a member of transcription factors that contain a highly-conserved winged helix DNA binding domain. RFX2 is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene.This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites.

Molecular Weight: 80 kDa

Gene ID: 5990

NCBI Accession: NP_000626

UniProt: P48378