KLF12 antibody

Catalog No. ABIN2458348

Product Details anti-KLF12 Antibody

Target: KLF12 (Kruppel-Like Factor 12 (KLF12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLF12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KLF12.

Application Details

Application Notes: KLF12 antibody can be used for detection of KLF12 by ELISA at 1:1562500. KLF12 antibody can be used for detection of KLF12 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store KLF12 antibody at -20 °C.

Target Details for KLF12

Target: KLF12 (Kruppel-Like Factor 12 (KLF12))

Alternative Name: KLF12 (KLF12 Products)

Synonyms: zgc:171689 antibody, KLF12 antibody, AP-2rep antibody, AP2REP antibody, 2700063E05Rik antibody, AI225908 antibody, AI315654 antibody, B130052C06Rik antibody, D530033K05Rik antibody, fb02h07 antibody, klf12 antibody, wu:fb02h07 antibody, zgc:77286 antibody, Kruppel-like factor 12b antibody, Kruppel like factor 12 antibody, Kruppel-like factor 12 antibody, Kruppel-like factor 12a antibody, klf12b antibody, KLF12 antibody, Klf12 antibody, klf12a antibody

Background: Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. KLF12 is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1.Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 44 kDa

Gene ID: 11278

NCBI Accession: NP_009180

UniProt: Q9Y4X4