MNT antibody

Catalog No. ABIN2458395

Product Details anti-MNT Antibody

Target: MNT (MNT, MAX Dimerization Protein (MNT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MNT antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MNT.

Application Details

Application Notes: MNT antibody can be used for detection of MNT by ELISA at 1:1562500. MNT antibody can be used for detection of MNT by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MNT antibody at -20 °C.

Target Details for MNT

Target: MNT (MNT, MAX Dimerization Protein (MNT))

Alternative Name: MNT (MNT Products)

Synonyms: MAD6 antibody, MXD6 antibody, ROX antibody, bHLHd3 antibody, etID309773.22 antibody, fb16b12 antibody, fb55f03 antibody, wu:fb16b12 antibody, wu:fb55f03 antibody, wu:fd06a08 antibody, wu:fz74f10 antibody, Rox antibody, Mnt antibody, zgc:165490 antibody, mnt antibody, rox antibody, MGC98824 antibody, MAX network transcriptional repressor antibody, max interactor 1, dimerization protein antibody, max binding protein antibody, MAX network transcriptional repressor b antibody, MAX network transcriptional repressor L homeolog antibody, MNT antibody, mxi1 antibody, Mnt antibody, mntb antibody, mnt.L antibody

Background: The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. MNT is a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molecular Weight: 62 kDa

Gene ID: 4335

NCBI Accession: NP_064706

UniProt: Q99583

Pathways: Chromatin Binding, Regulation of Muscle Cell Differentiation