GTSE1 antibody

Catalog No. ABIN2458657

Product Details anti-GTSE1 Antibody

Target: GTSE1 (G-2 and S-Phase Expressed 1 (GTSE1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTSE1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GTSE1.

Application Details

Application Notes: GTSE1 antibody can be used for detection of GTSE1 by ELISA at 1:1562500. GTSE1 antibody can be used for detection of GTSE1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GTSE1 antibody at -20 °C.

Target Details for GTSE1

Target: GTSE1 (G-2 and S-Phase Expressed 1 (GTSE1))

Alternative Name: GTSE1 (GTSE1 Products)

Synonyms: gtse1 antibody, MGC81588 antibody, MGC89498 antibody, GTSE1 antibody, fb70b04 antibody, fj88g09 antibody, wu:fb70b04 antibody, wu:fj88g09 antibody, wu:fy65d12 antibody, MGC114722 antibody, B99 antibody, Gtse-1 antibody, RGD1563164 antibody, G2 and S-phase expressed 1 S homeolog antibody, G2 and S-phase expressed 1 antibody, G-2 and S-phase expressed 1 antibody, G2 and S-phase expressed 1 L homeolog antibody, G two S phase expressed protein 1 antibody, gtse1.S antibody, gtse1 antibody, GTSE1 antibody, gtse1.L antibody, Gtse1 antibody

Background: GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.

Molecular Weight: 76 kDa

Gene ID: 51512

NCBI Accession: NP_057510

UniProt: Q9NYZ3