PHF12 antibody

Catalog No. ABIN2459410

Product Details anti-PHF12 Antibody

Target: PHF12 (PHD Finger Protein 12 (PHF12))

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHF12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PHF12.

Application Details

Application Notes: PHF12 antibody can be used for detection of PHF12 by ELISA at 1:312500. PHF12 antibody can be used for detection of PHF12 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PHF12 antibody at -20 °C.

Target Details for PHF12

Target: PHF12 (PHD Finger Protein 12 (PHF12))

Alternative Name: PHF12 (PHF12 Products)

Synonyms: PF1 antibody, 2410142K10Rik antibody, F630045O13 antibody, mKIAA1523 antibody, PHD finger protein 12 antibody, PHD finger protein 12 S homeolog antibody, PHF12 antibody, phf12 antibody, phf12.S antibody, Phf12 antibody

Background: PHF12 acts as a transcriptional repressor. It is involved in recruitment of functional SIN3A complexes to DNA. PHF12 represses transcription at least in part through the activity of an associated histone deacetylase (HDAC). IT may also repress transcription in a SIN3A-independent manner through recruitment of functional AES complexes to DNA.

Molecular Weight: 110 kDa

Gene ID: 57649

NCBI Accession: NP_001028733

UniProt: Q96QT6