ARG2 antibody

Catalog No. ABIN2459775

Product Details anti-ARG2 Antibody

Target: ARG2 (Arginase, Type II (ARG2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARG2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ARG2.

Application Details

Application Notes: ARG2 antibody can be used for detection of ARG2 by ELISA at 1:312500. ARG2 antibody can be used for detection of ARG2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ARG2 antibody at -20 °C.

Target Details for ARG2

Target: ARG2 (Arginase, Type II (ARG2))

Alternative Name: ARG2 (ARG2 Products)

Synonyms: AII antibody, AU022422 antibody, zgc:65793 antibody, zgc:85630 antibody, wu:fb67g02 antibody, ARG2 antibody, LeARG2 antibody, arg1 antibody, arg3 antibody, arg2 antibody, arg2-c antibody, arg2-b antibody, arginase 2 antibody, arginase type II antibody, arginase 2 L homeolog antibody, arginase 2 S homeolog antibody, ARG2 antibody, Arg2 antibody, arg2 antibody, arg2.L antibody, arg2.S antibody

Background: Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. ARG2 (type II isoform) is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood, it is thought to play a role in nitric oxide and polyamine metabolism.Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood, it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molecular Weight: 36 kDa

Gene ID: 384

NCBI Accession: NP_001163

UniProt: P78540