COLEC12 antibody

Catalog No. ABIN2460484

Product Details anti-COLEC12 Antibody

Target: COLEC12 (Collectin Sub-Family Member 12 (COLEC12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COLEC12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human COLEC12.

Application Details

Application Notes: COLEC12 antibody can be used for detection of COLEC12 by ELISA at 1:312500. COLEC12 antibody can be used for detection of COLEC12 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store COLEC12 antibody at -20 °C.

Target Details for COLEC12

Target: COLEC12 (Collectin Sub-Family Member 12 (COLEC12))

Alternative Name: COLEC12 (COLEC12 Products)

Synonyms: COLEC12 antibody, CLP1 antibody, NSR2 antibody, SCARA4 antibody, SRCL antibody, CL-P1 antibody, Scara4 antibody, hm:zeh0853 antibody, id:ibd2826 antibody, sb:cb377 antibody, si:ch211-212m21.5 antibody, collectin subfamily member 12 antibody, collectin sub-family member 12 antibody, COLEC12 antibody, colec12 antibody, Colec12 antibody

Background: COLEC12 encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor, a cell surface glycoprotein that can bind to carbohydrate antigens on microorganisms facilitating their recognition and removal. In addition, these receptors can recognize oxidized phospholipids so they may also participate in removing oxidatively damaged or apoptotic cells.

Molecular Weight: 82 kDa

Gene ID: 81035

NCBI Accession: NP_569057

UniProt: Q5KU26

Pathways: Activation of Innate immune Response