Hairless antibody

Catalog No. ABIN2460609

Product Details anti-Hairless Antibody

Target: Hairless (HR)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Hairless antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HR.

Application Details

Application Notes: HR antibody can be used for detection of HR by ELISA at 1:12500. HR antibody can be used for detection of HR by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store HR antibody at -20 °C.

Target Details for Hairless

Target: Hairless (HR)

Alternative Name: HR (HR Products)

Synonyms: ALUNC antibody, AU antibody, HSA277165 antibody, MUHH antibody, MUHH1 antibody, HR antibody, N antibody, ba antibody, bldy antibody, hr antibody, rh antibody, rh-bmh antibody, rhino antibody, HR, lysine demethylase and nuclear receptor corepressor antibody, hairless antibody, HR antibody, Hr antibody

Background: HR is a protein whose function has been linked to hair growth. A similar protein in rat functions as a transcriptional corepressor for thyroid hormone and interacts with histone deacetylases. Mutations in this gene have been documented in cases of autosomal recessive congenital alopecia and atrichia with papular lesions.

Molecular Weight: 127 kDa, 122 kDa

Gene ID: 55806

NCBI Accession: NP_005135

UniProt: O43593