CLCNKA antibody

Catalog No. ABIN2461106

Product Details anti-CLCNKA Antibody

Target: CLCNKA (Chloride Channel Ka (CLCNKA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLCNKA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CLCNKA.

Application Details

Application Notes: CLCNKA antibody can be used for detection of CLCNKA by ELISA at 1:62500. CLCNKA antibody can be used for detection of CLCNKA by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CLCNKA antibody at -20 °C.

Target Details for CLCNKA

Target: CLCNKA (Chloride Channel Ka (CLCNKA))

Alternative Name: CLCNKA (CLCNKA Products)

Synonyms: CLCNKA antibody, C75963 antibody, CLC-K1 antibody, Clcnk1 antibody, CLCK1 antibody, ClC-K1 antibody, hClC-Ka antibody, CLCNKB antibody, chloride voltage-gated channel Ka antibody, chloride channel protein ClC-Ka antibody, chloride channel, voltage-sensitive Ka antibody, CLCNKA antibody, LOC703259 antibody, LOC100456543 antibody, LOC100593875 antibody, Clcnka antibody

Background: CLCNKA is a member of the CLC family of voltage-gated chloride channels. It is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. This gene is a member of the CLC family of voltage-gated chloride channels. The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 75 kDa

Gene ID: 1187

NCBI Accession: NP_004061

UniProt: P51800

Pathways: Response to Water Deprivation