CREG1 antibody

Catalog No. ABIN2461706

Product Details anti-CREG1 Antibody

Target: CREG1 (Cellular Repressor of E1A-Stimulated Genes 1 (CREG1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CREG1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CREG1.

Application Details

Application Notes: CREG1 antibody can be used for detection of CREG1 by ELISA at 1:1562500. CREG1 antibody can be used for detection of CREG1 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CREG1 antibody at -20 °C.

Target Details for CREG1

Target: CREG1 (Cellular Repressor of E1A-Stimulated Genes 1 (CREG1))

Alternative Name: CREG1 (CREG1 Products)

Synonyms: CREG1 antibody, CREG antibody, AA755314 antibody, Creg antibody, cellular repressor of E1A stimulated genes 1 antibody, cellular repressor of E1A-stimulated genes 1 antibody, CREG1 antibody, creg1 antibody, Creg1 antibody

Background: The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. CREG1 antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro.The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation.

Molecular Weight: 24 kDa

Gene ID: 8804

NCBI Accession: NP_003842

UniProt: O75629