MAGEA9 antibody

Catalog No. ABIN2461754

Product Details anti-MAGEA9 Antibody

Target: MAGEA9 (Melanoma Antigen Family A, 9 (MAGEA9))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEA9 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MAGEA9.

Application Details

Application Notes: MAGEA9 antibody can be used for detection of MAGEA9 by ELISA at 1:62500. MAGEA9 antibody can be used for detection of MAGEA9 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MAGEA9 antibody at -20 °C.

Target Details for MAGEA9

Target: MAGEA9 (Melanoma Antigen Family A, 9 (MAGEA9))

Alternative Name: MAGEA9 (MAGEA9 Products)

Synonyms: CT1.9 antibody, MAGE9 antibody, MAGEA9B antibody, MAGEA9 antibody, MAGE family member A9 antibody, melanoma antigen family A, 9B antibody, melanoma-associated antigen 9 antibody, MAGEA9 antibody, MAGEA9B antibody, LOC525400 antibody

Background: MAGEA9 is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This pseudogene is a member of the cytochrome P450 gene superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. It is possible that, in rare cases, a combination of two SNPs in this gene may result in an open reading frame encoding a functional enzyme which metabolizes codeine to morphine. This locus is part of a cluster of cytochrome P450 genes on chromosome 22q13.1.

Molecular Weight: 35 kDa

Gene ID: 4108

NCBI Accession: NP_005356

UniProt: P43362