PEG3 antibody
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- Target See all PEG3 Antibodies
- PEG3 (Paternally Expressed 3 (PEG3))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PEG3 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by peptide affinity chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PEG3.
- Top Product
- Discover our top product PEG3 Primary Antibody
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- Application Notes
- PEG3 antibody can be used for detection of PEG3 by ELISA at 1:312500. PEG3 antibody can be used for detection of PEG3 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store PEG3 antibody at -20 °C.
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- Target
- PEG3 (Paternally Expressed 3 (PEG3))
- Alternative Name
- PEG3 (PEG3 Products)
- Synonyms
- PW1 antibody, ZKSCAN22 antibody, ZNF904 antibody, ZSCAN24 antibody, AL022617 antibody, ASF-1 antibody, End4 antibody, Gcap4 antibody, Pw1 antibody, Zfp102 antibody, mKIAA0287 antibody, PEG3 antibody, paternally expressed 3 antibody, paternally-expressed gene 3 protein antibody, PEG3 antibody, Peg3 antibody, LOC100448879 antibody
- Background
- PEG3 induces apoptosis in cooperation with SIAH1A and acts as a mediator between TP53/p53 and BAX in a neuronal death pathway that is activated by DNA damage. PEG3 acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B. PEG3 also possesses a tumor suppressing activity in glioma cells.
- Molecular Weight
- 181 kDa
- Gene ID
- 5178
- NCBI Accession
- NP_006201
- UniProt
- Q9GZU2
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