PSMA6 antibody

Catalog No. ABIN2462130

Product Details anti-PSMA6 Antibody

Target: PSMA6 (Proteasome Subunit alpha 6 (PSMA6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMA6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PSMA6.

Application Details

Application Notes: PSMA6 antibody can be used for detection of PSMA6 by ELISA at 1:312500. PSMA6 antibody can be used for detection of PSMA6 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PSMA6 antibody at -20 °C.

Target Details for PSMA6

Target: PSMA6 (Proteasome Subunit alpha 6 (PSMA6))

Alternative Name: PSMA6 (PSMA6 Products)

Synonyms: IOTA antibody, PROS27 antibody, p27K antibody, psma6 antibody, psma6b antibody, zgc:91778 antibody, proteasome subunit alpha 6 antibody, proteasome (prosome, macropain) subunit, alpha type 6 antibody, proteasome subunit alpha 6a antibody, proteasome subunit alpha 6 L homeolog antibody, proteasome subunit alpha 6, like antibody, PSMA6 antibody, Psma6 antibody, psma6a antibody, psma6.L antibody, psma6l antibody

Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA6 is a member of the peptidase T1A family, which is a 20S core alpha subunit.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molecular Weight: 27 kDa

Gene ID: 5687

NCBI Accession: NP_002782

UniProt: P60900

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA