STS antibody

Catalog No. ABIN2462461

Product Details anti-STS Antibody

Target: STS (Steroid Sulfatase (Microsomal), Isozyme S (STS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STS antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human STS.

Application Details

Application Notes: STS antibody can be used for detection of STS by ELISA at 1:312500. STS antibody can be used for detection of STS by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store STS antibody at -20 °C.

Target Details for STS

Target: STS (Steroid Sulfatase (Microsomal), Isozyme S (STS))

Alternative Name: STS (STS Products)

Synonyms: ARSC antibody, ARSC1 antibody, ASC antibody, ES antibody, SSDD antibody, XLI antibody, abcg2 antibody, ArsC antibody, Sts antibody, si:ch211-271l9.1 antibody, steroid sulfatase antibody, breast cancer resistance protein antibody, Steryl-sulfatase antibody, steryl-sulfatase antibody, steroid sulfatase (microsomal), isozyme S antibody, STS antibody, abcg2 antibody, Sts antibody, Plav_0360 antibody, Psta_3963 antibody, Runsl_5106 antibody, LOC100712701 antibody, sts antibody

Background: STS catalyzes the conversion of sulfated steroid precursors to estrogens during pregnancy. The protein is found in the endoplasmic reticulum, where it acts as a homodimer. Mutations in its gene are known to cause X-linked ichthyosisThe protein encoded by this gene catalyzes the conversion of sulfated steroid precursors to estrogens during pregnancy. The encoded protein is found in the endoplasmic reticulum, where it acts as a homodimer. Mutations in this gene are known to cause X-linked ichthyosis (XLI).

Molecular Weight: 64 kDa

Gene ID: 412

NCBI Accession: NP_000342

UniProt: P08842

Pathways: Steroid Hormone Biosynthesis