SBDS antibody

Catalog No. ABIN2462891

Product Details anti-SBDS Antibody

Target: SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))

Reactivity: Human, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SBDS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SBDS.

Application Details

Application Notes: SBDS antibody can be used for detection of SBDS by ELISA at 1:62500. SBDS antibody can be used for detection of SBDS by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SBDS antibody at -20 °C.

Target Details for SBDS

Target: SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))

Alternative Name: SBDS (SBDS Products)

Synonyms: cgi-97 antibody, sds antibody, swds antibody, zgc:56700 antibody, SDS antibody, SWDS antibody, 4733401P19Rik antibody, AI836084 antibody, CGI-97 antibody, SBDS ribosome assembly guanine nucleotide exchange factor antibody, hypothetical protein antibody, SBDS, ribosome maturation factor antibody, SBDS ribosome assembly guanine nucleotide exchange factor S homeolog antibody, SBDS ribosome maturation factor antibody, sbds antibody, LOAG_04440 antibody, sbds.S antibody, SBDS antibody, Sbds antibody

Background: SBDS is a member of a highly conserved protein family that exists from archaea to vertebrates and plants. The protein may function in RNA metabolism. Mutations within its gene are associated with Shwachman-Bodian-Diamond syndrome.This gene encodes a member of a highly conserved protein family that exists from archaea to vertebrates and plants. The encoded protein may function in RNA metabolism. Mutations within this gene are associated with Shwachman-Bodian-Diamond syndrome. An alternative transcript has been described, but its biological nature has not been determined. This gene has a closely linked pseudogene that is distally located.

Molecular Weight: 28 kDa

Gene ID: 51119

NCBI Accession: NP_057122

UniProt: Q9Y3A5

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly