ALDOA antibody

Catalog No. ABIN2463134

Product Details anti-ALDOA Antibody

Target: ALDOA (Aldolase A, Fructose-Bisphosphate (ALDOA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDOA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ALDOA.

Application Details

Application Notes: ALDOA antibody can be used for detection of ALDOA by ELISA at 1:62500. ALDOA antibody can be used for detection of ALDOA by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ALDOA antibody at -20 °C.

Target Details for ALDOA

Target: ALDOA (Aldolase A, Fructose-Bisphosphate (ALDOA))

Alternative Name: ALDOA (ALDOA Products)

Synonyms: ALDA antibody, GSD12 antibody, aldoa antibody, cb79 antibody, sb:cb79 antibody, wu:fa28b10 antibody, wu:fb10b11 antibody, ALDOA antibody, Aldo-1 antibody, Aldo1 antibody, RNALDOG5 antibody, hm:zeh0036 antibody, zgc:77696 antibody, aldolase, fructose-bisphosphate A antibody, aldolase a, fructose-bisphosphate, a antibody, aldolase, fructose-bisphosphate A S homeolog antibody, aldolase A, fructose-bisphosphate antibody, aldolase a, fructose-bisphosphate, b antibody, ALDOA antibody, aldoaa antibody, aldoa antibody, aldoa.S antibody, Aldoa antibody, aldoab antibody

Background: ALDOA is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia.This gene product, Aldolase A (fructose-bisphosphate aldolase) is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants which encode the same protein.

Molecular Weight: 39 kDa

Gene ID: 226

NCBI Accession: NP_000025

UniProt: P04075

Pathways: Ribonucleoside Biosynthetic Process