CD46 antibody

Catalog No. ABIN2480634

This Mouse Monoclonal antibody specifically detects CD46 in WB, FACS, IF, IP and Func. It exhibits reactivity toward Human and has been mentioned in 3+ publications.

Quick Overview for CD46 antibody (ABIN2480634)

Target: CD46

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD46 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Functional Studies (Func)

Clone: MEM-258

Product Details anti-CD46 Antibody

Characteristics: Purified IgG

Purification: Purified

Immunogen: HPB-ALL cell line

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

References for anti-CD46 antibody (ABIN2480634)

Fremeaux-Bacchi, Moulton, Kavanagh, Dragon-Durey, Blouin, Caudy, Arzouk, Cleper, Francois, Guest, Pourrat, Seligman, Fridman, Loirat, Atkinson: "Genetic and functional analyses of membrane cofactor protein (CD46) mutations in atypical hemolytic uremic syndrome." in: Journal of the American Society of Nephrology : JASN, Vol. 17, Issue 7, pp. 2017-25, (2006) (PubMed).

Fleischli, Verhaagh, Havenga, Sirena, Schaffner, Cattaneo, Greber, Hemmi: "The distal short consensus repeats 1 and 2 of the membrane cofactor protein CD46 and their distance from the cell membrane determine productive entry of species B adenovirus serotype 35." in: Journal of virology, Vol. 79, Issue 15, pp. 10013-22, (2005) (PubMed).

Sirena, Lilienfeld, Eisenhut, Kälin, Boucke, Beerli, Vogt, Ruedl, Bachmann, Greber, Hemmi: "The human membrane cofactor CD46 is a receptor for species B adenovirus serotype 3." in: Journal of virology, Vol. 78, Issue 9, pp. 4454-62, (2004) (PubMed).

Target Details for CD46

Target: CD46

Alternative Name: CD46

Background: Synonyms: MEMBRANE CO-FACTOR PROTEIN

Gene ID: 4179

UniProt: P15529

Pathways: Regulation of Actin Filament Polymerization